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The main purpose of the small intestine is to digest and absorb food into the body. The small bowel, also known as the small intestine, is the part of the gastrointestinal tract that connects the stomach with the colon. It has been theorized that SIBO may be responsible for the symptoms of at least some people diagnosed with irritable bowel syndrome. There is a striking similarity between the symptoms of irritable bowel syndrome ( IBS) and SIBO. There are many conditions associated with SIBO including diabetes, scleroderma, Crohn's disease, and others. Too many of these acids can result in neurological dysfunction.Small intestinal bacterial overgrowth (SIBO) refers to a condition in which abnormally large numbers of bacteria (usually defined as at least 100,000 bacteria per ml of fluid) are present in the small intestine, and the types of bacteria in the small intestine resemble more the bacteria of the colon than the small intestine.
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Other consequences can arise due to overgrowth of bacteria which produce a range of acids.
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Problems outside the gut such as joint pains, skin problems, headaches and even autoimmune diseases may be consequences. It is believed that this can trigger a reaction by the immune system to start attacking food particles in the bloodstream as if they were pathogenic toxins. Damage to zonulin is a contributing factor to leaky gut or increased intestinal permeability. Low-level inflammation (not a lot – after all, these are normal bacteria) can cause damage to the lining of the small intestine – particularly to a protein called zonulin. This generally leads to food intolerance of greater or lesser degrees. A damaged brush border has a significantly detrimental impact on digestion and absorption of nutrients. SIBO damages the tiny hair-like structures (known as villi) that line the intestinal tract – creating a “brush border”. You may also have trouble maintaining a healthy body weight. Associated with poor fat absorption is deficiencies in vitamins A, E, and K (and sometimes D), as these are all fat-soluble vitamins. You might have urgent diarrhoea (especially in the morning), fatty stool, or feel nauseated when you eat a high-fat food. You may also have deficiencies in some vitamins and other nutrients due to bacteria interfering with absorption or even consuming some of your nutrients for themselves. As a result, if you have SIBO, you could have problems digesting carbohydrates (bread, pasta, pototoes, possibly fruit, and other sweet things). That’s because the bacteria break apart sugars and carbohydrates along the lining of the small intestine. When there are too many bacteria in the small intestine, digestion suffers.